During the Ming and Qing Dynasties, important academic transformation took place in the ideological circle. Because at that time, most scholars had the judgment that the Ming Dynasty died because of Wang Yangming's theories, and then the ideological movement of venerating Zhu Xi and censuring Wang Yangming was launched. Therefore, the mainstream of academic study in the early Qing Dynasty gradually turned from Yangming School to Zhu Xi School. Among the scholars in Zhu Xi School then, Lv Liuliang and Lu Longqi, both from western Zhejiang, had played an important role in promoting it for the development of the movement. Both Lv Liuliang and Lu Longqi tried their best to interpret and analyze the book written by Zhu Xi Sishuzhangjujizhu. In their relevant works, there were many criticisms against Yang Ming's theories, and they mainly focused on Four-sentence Doctrine which Wang Yangming advocated in his later years. They believed that there were two ways to guide students to become saints, and the essence of human morality did not contain any goodness or evil. Both of Wang Yangming's theories belonged to Zen thought. By further analyzing the relationship between mind and human nature or heaven, they pointed out that the philosophy of the mind was the heresy which originates the mind, and neo-confucianism was the real Confucianism which originates from the principle of nature. Only when human nature and heaven were integrated, could we truly achieve the goal of moral cultivation of goodness and no evil. For knowing about how to understand Yangming School and how to promote academic transformation, it is of important significance to discuss Lv Liuliang and Lu Longqi's analysis about Wang Yangming's Four-sentence Doctrine.