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Recurrent Multiple Strokes in a Lupus Patient with Antiphospholipid Antibodies:A Case Report

反覆性多發腦中風與抗磷脂抗體陽性紅斑性狼瘡-病例報告

摘要


一位44歲患有狼瘡的女性病人因為間歇性的高燒而入院而且因為血液培養陽性而被診斷為敗血症,風濕病系列檢查顯示抗核抗體抗去氧核糖核酸抗體及抗牛心脂抗體指數皆上升,住院期間,病人覺得視力變模糊而且感覺頭痛,因此做了核磁共振檢查顯示有多處腦栓塞,雖然經過類固醇與抗血小板凝集藥物的治療,她仍然在9個月後又發生第二次腦中風,們針對腦中風與抗磷脂抗體導致栓塞的相關性及有關論文做一個回顧及討論。

並列摘要


A 44-year-old female patient was admitted to the hospital because of intermittent high fever. Sepsis was diagnosed from a blood culture. Rheumatological profiles showed high anti-nuclear, anti-dsDNA and anticardiolipin antibody titers. During hospitalization, the patient complained of blurred vision and headache. MR imaging showed multiple infarcts. In spite of corticosteroid and antiplatelet treatment, she developed the second stoke and died nine months after admission. The strokes may have been caused by antiphospholipid antibody-related thrombosis. The association of stroke with such thrombosis is discussed in medical reviews.

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