- 期刊
Audiovestibular Symptoms in a Case of Primary Intraocular Lymphoma with Brainstem Metastasis - A Case Report
原發性眼內淋巴瘤併腦幹轉移病例之聽覺前庭症狀－病例報告
摘要
原發性眼內淋巴瘤是一罕見疾病，常伴隨有中樞神經系統侵犯，但是罕以眩暈為中樞神經系統侵犯之主要表徵。本文報告一名70歲患有原發性眼內淋巴瘤之女性患者，在接受放射線治療3個月後，發生持續眩暈、兩二耳聽力喪失、左側偏癱以及方向變換性頭位眼振。核磁共振檢查發現左側中小腦角有一病變。腦脊髓液的細胞學檢查發現淋巴癌細胞，證實中樞神經系統轉移。故當淋巴瘤病人出現持續眩暈、聽力喪失、以及中樞性眼振時，必須安排核磁共振以及腦脊液檢查排除中樞神經系統轉移的可能性。
並列摘要
Primary intraocular lymphoma, a rare disease, is frequently associated with central nervous system involvement, but it rarely pre-sents with inner ear symptoms. This paper reports a 70-year-old woman with primary intraocular lymphoma who experienced persistent vertigo, bilateral hearing loss, left hemiparesis, and direction-changing positional nystagmus three months after irradiation. An MRI scan depicted a space-occupying lesion in the left middle cerebellar peduncle and cytologic study of the cerebrospinal fluid disclosed lymphoma cells. Therefore, when a lymphoma patient experiences persistent vertigo, hearing loss, and central type nystagmus, an MRI and cerebrospinal fluid cytologic examinations should be performed to exclude the possibility of CNS involve-ment.
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