Clinical Applications of Nailfold Capillaroscopy in Different Rheumatic Diseases

甲褶微血管顯微鏡（甲褶鏡）在風濕性疾病的應用與角色

林科名(Ko-Ming Lin) ； 鄭添財(Tien-Tsai Cheng) ； 陳忠仁(Chung-Jen Chen)

《內科學誌》 20卷3期 (2009/06) Pp. 238-247

https://doi.org/10.6314/JIMT.2009.20(3).07

摘要

末梢血管病變和全身性發炎疾病的關係密不可分。其中屬於風濕性疾病的雷諾氏症和硬皮症的微血管變化更是明顯異常。而甲褶鏡是一種用顯微放大原理來觀察手指末端微血管變化的一種檢查方式。它對於評估風濕病的微循環可以是非侵入性、方便、簡單、可重覆以及高敏感度的一種檢查。借藉由輔以新式影像攝影系統，甲褶鏡更容易及清楚的分析微血管變化。目前，對用在鑑別原發性或次發性雷諾氏症、硬皮症、皮肌炎的輔助診斷和全身性紅斑狼瘡的疾病活性變化等都有一定價值。因此本文藉由文獻回顧來分析微血管變化和風濕病的關係。

並列摘要

Microvascular involvement in systemic inflammatory diseases has been well known more than one hundred years. Abnormal microangiopathy of nailfold often occurs in systemic rheumatic diseases, especially in scleroderma, Raynaud's phenomenon and related conditions. Nailfold capillaroscopy uses a lens that allows analysis of the capillary morphology and microcirculation of nailfold. Recently, the video-base or computer-base system of capillaroscopy is developed and it is used as a noninvasive, simple, repeatable, highly sensitive and inexpensive method of evaluating microvascular abnormalities in rheumatic diseases. This review stresses the importance and advantages of NFC for investigating microvascular morphological patterns and their clinical correlations in rheumatic diseases.

並列關鍵字

Nailfold capillaroscopy ； Raynaud's phenomenon ； Systemic sclerosis