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Ampulla Cardiomyopathy (Takotsubo Cardiomyopathy)-A Review

壺腹形心肌病變-文獻回顧

摘要


壺腹形心肌病變又稱爲壓力性心肌病變或中斷性心臟徵候群(broken heart syndrome),臨床症狀與急性冠心症相仿。病人會有短暫性左心室尖端及心室中段等部位收縮功能缺損,同時合併基部收縮過度。病生理學在最近幾年已被使用心臟核子醫學攝影廣泛所研究。致病機轉可能與兒茶酚胺或腎上腺受體過度活化所造成之心肌病變有關,但也有可能是多發性的。在本文中我們回顧文獻中有關此疾病之盛行率、可能致病因、危險因子、心電圖及心臟超音波特徵、臨床表現、診斷準則、預後及治療。

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並列摘要


The ampulla cardiomyopathy (Takotsubo Cardiomyopathy) also known as stress-induced cardiomyopathy (SICD), or broken heart syndrome, mimics acute coronary syndrome, typically characterized by transient regional systolic dysfunction involving the left ventricle apex and midventricle with hyperkinesis of the basal segments. Pathophysiology of this disease has been investigated by myocardial scintigraphy in recent years. The etiology may be related to catecholaminergic or adrenoceptor-hyperactive cardiomyopathy, but also may be mutlifactoral. In this article, we provide a brief review of the literature regarding the prevalence, the possible etiology, risk factors, electrocardiographic and echocardiographic findings, clinical manifestation, diagnostic criteria, prognosis and treatment.

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