- 期刊
Good's Syndrome Complicated by Repetitive ＂Campylobacter Jejuni＂ Sepsis and Cellulitis
古德綜合症併發反覆的空腸曲狀桿菌敗血症和蜂窩性組織炎
摘要
空腸曲狀桿菌很少引起菌血症或腸道外的感染。我們報導一位患有古德綜合症的病患，其遭受了空腸曲狀桿菌蜂窩性組織炎及敗血症的反覆感染，其中間隔有將近一年之久未發病。血清學檢查顯示低丙球蛋白血症，淋巴細胞亞群的分析並且發現，帶有CD20+及CD4+細胞標誌物的比例皆顯著的降低。脈衝式膠體電泳顯示存在於此患者中的微生物屬於同源菌株，其表示了空腸彎曲桿菌的潛伏感染。蜂窩組織炎和敗血症的反覆發作反映了這種難以治療的感染之臨床特性。
關鍵字
無資料並列摘要
Campylobacter jejuni rarely causes bacteremia or extraintestinal infection. We report a case with Good's syndrome suffering from repetitive cellulitis and sepsis associated with C. jejuni that relapsed after a disease-free interval of almost one year. Serological examination demonstrated hypogammaglobulinemia, and analysis of lymphocyte subsets showed marked decreases in proportion of cells bearing both CD20+ and CD4+ cell markers. Pulsed field gel electrophoresis showed that the microorganisms in this patient were the same bacterial strain, and indicated a latent C. jejuni infection. The repetitiveness of cellulitis and sepsis was reflected in the clinical properties of this difficult-to-treat infection.
延伸閱讀
- Wang, L., Hong, K. C., Lin, F. C., & Yang, K. D. (2003). 黴漿菌感染關連史蒂芬瓊森症候群之病例呈現淋巴球低下以及CD4＋T淋巴球之重新分佈. Journal of the Formosan Medical Association, 102(1), 55-58. https://doi.org/10.29828/JFMA.200301.0012
- 陳姿伶（2010）。梨形蟲感染排除後之小鼠腸道呈現持續性上皮屏障失常及黏膜發炎的現象：探討「後感染腸躁症」之致病機轉〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2010.01491
- Wang, Y. C., Lin, C. M., & Chen, S. K. (2016). 社區型的抗藥性金黃色葡萄球菌導致之攝護腺膿瘍：二病例報告及文獻回顧. 輔仁醫學期刊, 14(4), 205-212. https://doi.org/10.3966/181020932016121404004
- Hsu, C. H., Yang, Y. H., Tasi, C. H., Wu, H. S., Hung, M. C., Wu, Y. J., Chou, D. A., Yang, J. C., & Huang, M. H. (2007). Peutz-Jeghers症候群引起腸套疊個案報告. 秀傳醫學雜誌, 7(3), 111-114. https://www.airitilibrary.com/Article/Detail?DocID=15610497-200710-7-3-111-114-a
- Lin, W. J., Lai, Y. S., Lo, W. T., Hung, C. H., Cheng, S. N., & Wang, C. C. (2004). b型流行性感冒嗜血桿菌引起的蜂窩組織炎：二病例報告. Acta Paediatrica Taiwanica, 45(2), 100-103. https://doi.org/10.7097/APT.200404.0100