微弧氧化前處理及冷電漿接枝聚合表面改質鈦金屬其生物適應性之研究

Biocompatibility of Post Treatment Micro-arc Oxidation Titanium Surface Modified by Cold Plasma and Surface Graft Polymerization

廖淑娟(Shu-Chuan Liao) ； 張嘉玓(Chia-Ti Chang) ； 陳克紹(Ko-Shao Chen)

《真空科技》 27卷3期 (2014/09) Pp. 22-28

摘要

鈦及鈦合金具有良好的機械、耐蝕及質量輕等特性，廣泛應用於支架、骨板和骨板等植入物，當金屬材料植入人體時，人體的免疫系統會攻擊植入物表面，因此必須考慮金屬表面之抗腐蝕性及生物相容性。本研究以純鈦金屬為基材，先以微弧氧化處理使表面形成多孔陶瓷層並提升其腐蝕及耐磨等特性，利用冷電漿沉積六甲基二矽胺烷薄膜再以氧氣電漿活化其表面，以此具有自由基及過氧化基的表面作為界面層，即可以使用UV光誘導接枝聚合機能性有機高分子丙烯酸單體，最後再以交聯劑固定多醣類高分子於表面獲得生物適應膜。由實驗結果可知經由微弧氧化處理後基材表面呈親水性，其水接觸角由63度下降至0~15度左右，而經電漿及接枝高分子之水接觸角亦有變化。由極化曲線得知微弧氧化及電漿表面改質鈦的耐腐蝕性最佳且生物相容性亦有改善。

關鍵字

微弧氧化 ； 冷電漿 ； 生物適應性

並列摘要

The metal materials are used widely for implants such as stent and lamellae. However, the immune system will attack the surface of implants when it implants in human beings. So far, the corrosion resistance and biocompatibility of surface is the most important topic for implant materials. In this study, the corrosion resistance of Ti surface was improved by plasma deposition of hexamethyldisilazane (HMDSZ) and micro-arc oxidation. In order to immobilize the bio-molecular by crosslinking, the carboxyl functional group which was produced from oxygen plasma surface activation and graft polymerization of acrylic acid (AAc) were activated. The water contact angle of the micro-arc oxidation Ti decreases from 63° to 0~15°, which is hydrophilic. The results of electrochemical polarization analysis showed that the sample treated at micro-arc oxidation and plasma treatment has the best corrosion resistance.

並列關鍵字

micro-arc oxidation ； cold plasma ； biocompatibility