中藥“清鼻散”治療小兒過敏性鼻炎之研究

The Therapeutic Effect of Chinese Medical Preparation "Qing Bi San" on Allergic Rhinitis

蔡順輝(Shun-Hui Tsai)

《中醫藥雜誌》 6卷1期 (1995/03) Pp. 27-36

https://doi.org/10.6940/JCM.199503_6(1).03

摘要

Though the Western medical understanding of the pathogenesis and treatment of allergic rhinitis has improved greatly through recent years, Western medication causes certain side-effects. It is our hope to find a solution from traditional Chinese medicine.
The study covers 48 children diagnosed as suffering from allergic rhinitis by the Department of Traditional Pediatrics of the China Medical College Hospital from Oct. 1993 to May 1994. There were 26 males and 22 females. Their ages ranged from 6 to 11 with an average of 8.1. According to Chinese medical pattern identification, 28 of them displayed heat-predominant patterns and 20 of them displayed cold-predominant patterns. They were treated with a Chinese medical preparation ”qing bi san”, (comprising ”xin-yi qing fei yin” plus ”zhi bo di-huang wan”) for 12 weeks. After the treatment, the heat-predominant pattern patients improved in subjective symptoms including nasal obstruction, rhinorrhea, sneezing and itching. The degree of hypertrophy of nasal turbinates showed statistically significant decrease. In laboratory data, they showed significant decrease (p＜0.05) in total eosinophil count and nasal eosinophilia. They showed, however, no significant difference in serum IgE value and Mite DPT, and Mite DF indexes gained through QUIDEL Reflectance Analyzer. On the other hand, the cold-predominant pattern patients revealed no improvement in signs & symptoms nor in laboratory data after the treatment. There were no side effects except temporary stomach fullness and pain in 6 cases, which can be attributed to the medication.
Clearly, this study concludes that the application of traditional Chinese pattern identification in diagnosis, combined with Chinese formula in treatment of allergic rhinitis is effective, as far as the heat-predominated pattern patients is concerned.

關鍵字

過敏性鼻炎 ； 中藥 ； 清鼻散

並列摘要

Though the Western medical understanding of the pathogenesis and treatment of allergic rhinitis has improved greatly through recent years, Western medication causes certain side-effects. It is our hope to find a solution from traditional Chinese medicine.
The study covers 48 children diagnosed as suffering from allergic rhinitis by the Department of Traditional Pediatrics of the China Medical College Hospital from Oct. 1993 to May 1994. There were 26 males and 22 females. Their ages ranged from 6 to 11 with an average of 8.1. According to Chinese medical pattern identification, 28 of them displayed heat-predominant patterns and 20 of them displayed cold-predominant patterns. They were treated with a Chinese medical preparation ”qing bi san”, (comprising ”xin-yi qing fei yin” plus ”zhi bo di-huang wan”) for 12 weeks. After the treatment, the heat-predominant pattern patients improved in subjective symptoms including nasal obstruction, rhinorrhea, sneezing and itching. The degree of hypertrophy of nasal turbinates showed statistically significant decrease. In laboratory data, they showed significant decrease (p＜0.05) in total eosinophil count and nasal eosinophilia. They showed, however, no significant difference in serum IgE value and Mite DPT, and Mite DF indexes gained through QUIDEL Reflectance Analyzer. On the other hand, the cold-predominant pattern patients revealed no improvement in signs & symptoms nor in laboratory data after the treatment. There were no side effects except temporary stomach fullness and pain in 6 cases, which can be attributed to the medication.
Clearly, this study concludes that the application of traditional Chinese pattern identification in diagnosis, combined with Chinese formula in treatment of allergic rhinitis is effective, as far as the heat-predominated pattern patients is concerned.

並列關鍵字

Allergic rhinitis ； Traditional Chinese medicine ； Qing Bi San