This paper analyzes the long-run effect of a permanent rise in the rate of money growth on economic growth and the depreciation rate. We also explore how indeterminacy is affected by the degree of currency substitution. It is shown that the elasticity of currency substitution plays a decisive role in the economic growth effects of monetary policy. Relatively higher money growth will result in a higher (lower) economic growth rate if the elasticity of currency substitution is larger (less) than one; while it raises the depreciation rate, regardless of whether currencies are substitutable or complementary. In addition, we also find that local indeterminacy is more likely to appear if the elasticity of currency substitution is larger.