Previously, the direct assessment of regional heart wall motion required invasive methods such as the implantation of pulse transit sonomicrometry crystal or fluoruscopically trackable metallic marks within the myocardium. Their applicability in human studies was therefore limited, even the 2-D cardioechography applied since the end of 1970's had limitation in identifying endocardial and epicardial boundaries and measuring cavity dimension and wall thickening. MRI has been used since recent years to assess the regional heart wall motion because of its possible potential in the study of cardiovascular disease. Being great potential in the study of cardiovascular disease, MRI has been used to assess the regional heart wall motion. We tried to use the tagging technique of SPAMM (spatial modulation of magnetization), created by Dr. Leon Axel in 1989, to produce images with a regular pattern of stripes that moves with the heart wall and to permit the use of a 2-D grid of stripes for more detailed studies of heart wall motion. It provides a unique method of analyzing regional heart wall strain.
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