Life-Threatening Reactions with Ionic Contrast Medium: A Six-Year Experience

離子性顯影劑的嚴重反應（六年經驗）

彭國權(Kwok Kuen Pang) ； 楊斐適(Fi-Sh Yang) ； 葉宏一(Hung-I Yeh) ； 馬玉章(Yei-Chang Ma)

《中華放射線醫學雜誌》 19卷3期 (1994/09) Pp. 203-208

摘要

人體對注入血管的顯影劑，會有某些相當嚴重的反應。在我們的伍仟肆佰參拾壹個病人中發生可致命反應的有五個例子占0•09%；較顯著的如：血管陷落性循環不足、心跳停止、急性心肌梗塞，及過敏性休克。60%可急救成功。致死的有二個例子占0•037%其中一病例在注射顯影劑的當時即獰死，另一病例在急救成功後至加護病房三天後死亡。顯影劑引起的致命反應通常並無先兆，反應開始的愈早，急救的成功率愈低。而在使用顯影劑前之測試是不可靠且多餘的。一般說來致命的反應較易發生在七十歲以上，併有心肺功能不足的老人。所以非離子性顯影劑對於年長的、心肺不足的及有過敏病史的病人特別適用。

關鍵字

顯影劑 ； 顯影劑，併發症 ； 顯影劑，作用

並列摘要

Serious reactions to intravascular contrast medium are described. Predominant findings were vascular collapse, asystole, acute myocardial infarction and anaphylactoid reaction. The incidence of life-threatening reactions was 5 out of 5431 cases or 0.09%. The highest incidence, was in the 70-year-old group. Immediate successful resuscitation rate was 80%; overall successful resuscitation is 60%. Fatal reactions to contrast medium occur often without warning, and the earlier the reaction occurs, the less likelihood of successful resuscitation. The mortality rate was 2/5431 cases, or 0.037%. One patient died immediately during contrast administration, while another developed serious reaction during the contrast injection but death was delayed for three days with intensive medical treatment. Elderly patients with cardiopulmonary compromise status are most susceptible. For this reason, it is recommended that nonionic contrast medium be used for elderly patients, for the high risk group with cardiopulmonary disorders or for patients with a history of allergy.

並列關鍵字

Contrast media ； contrast media, complication ； contrast media, effects