嗅神經母細胞瘤－8例分析

Esthesioneuroblastoma-An Analysis of 8 Cases

陳記得(Kee-Tak Chan) ； 林清榮(Ching-Zong Lin)

《台灣耳鼻喉頭頸外科雜誌》 40卷4期 (2005/08) Pp. 135-138

https://doi.org/10.6286/2005.40.4.135

摘要

背景：嗅神經母細胞瘤為鼻腔罕見的腫瘤。本文說其症狀、分期、治療模式與預後加以分析。
方法：從1970年到1990年，本科共經歷8例，作為分析對象。
結果：男性5例，女性3例。平均年齡41.9歲。臨床症狀依次為鼻塞(50%)、鼻溢(37.5%)、鼻衂(25%)、頸部腫塊(25%)、與眼球突出(12.5%)。4例早期、4例晚期。治療以手術加上術後放射療法為主。已有7例死亡。
結論：嗅神經母細胞瘤不易早期診斷。手術合併放射療法是基本的治療模式。晚期轉移導致治療失敗。

關鍵字

嗅神經母細胞瘤 ； 顱顏切除術

並列摘要

BACKGROUND: Olfactory neuroblastoma is a rare tumor in nasal cavities. This study retrospectively reviewed its symptoms, stage, treatment modalities and prognosis.
METHODS: There were 5 males and 3 females with a mean age of 41.9 years. Clinical manifestations were nasal obstruction (50%), rhinorrhea (37.5%), epistaxis (25%), neck mass (25%) and exophthalmos (12.5%). There were 4 early cases (stageA/B) and 4 late cases (stage C). Surgery combined with postoperative radiotherapy was the main treatment modality. Seven cases were expired.
CONCLUSION: It is difficult to early diagnose this tumor. Surgery combined with postoperative radiotherapy is the main treatment modality. Local and distant metastasis result in treatment failure.

並列關鍵字

esthesioneuroblastoma ； craniofacial resection