摘要
原發性甲狀腺淋巴瘤是一種不常見的腫瘤，約佔所有甲狀腺惡性腫瘤的5%、佔所有淋巴結外淋巴瘤的2.5%至7%。大部分發生在中年至老年的婦女。而且約27%至100%的病人有橋本氏甲狀腺炎的過去史，治療方式依組織學型態及臨床分期，有放射治療、化學治療或合併治療。奇美醫院耳鼻喉科於2002年8月經歷1例49歲女性，主訴前頸部有1個10cm以上的巨大腫塊，於3個月內迅速長大，病人在接受腫瘤部分切除手術後，病理診斷為原發性甲狀腺淋巴瘤。組織型態為瀰漫性巨大型B細胞淋巴瘤。病人接受6次CEOP (endoxan, epirubicin, oncovin, prednisolone)化學治療後，至2006年4月已經3年8個月，並無局部復發或遠處轉移的現象。
並列摘要
Primary thyroid lymphoma, an uncommon tumor representing approximately 5% of all thyroid malignant neoplasms and 2.5% to 7% of all extranodal lymphomas, typically occurs in middle- to old-aged women, 27% to 100% of whom is with the past history of Hashimoto's thyroiditis. The histological pattern- and clinical stage-based treatment covered radiation therapy, chemotherapy and combined therapy. A 49-year-old woman with a chief complaint of an over 10 cm lump rapidly growing within 3 months visited the Department of Otolaryngology of Chi-Mei Medical Center in August, 2002. After partial excision, the said lymphoma whose histological pattern was diffuse large B cell lymphoma was diagnosed by frozen section and pathology. Consequently, after 6 courses of chemotherapy with CEOP (endoxan, epirubicin, oncovin, prednisolone), there has been no evidence of local recurrence or distant metastasis manifested.
延伸閱讀
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