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摘要


大細胞未分化癌(large cell undifferentiated carcinoma)在腮腺惡性腫瘤是相當少見的,組織病理的特徵是診斷的依據,先要排除從肺部轉移來的可能性,手術切除加上術後放射治療是主要治療方式,但預後都不太好。1名66歲女性因右側耳下方有一腫塊,頭頸電腦斷層顯示在右側腮腺有一高密度的腫塊且有2-3顆的腮腺淋巴結,病人接受腮腺全切除手術,組織病理與免疫組織化學檢查顯示爲大細胞未分化癌,病人接受術後放射治療,追蹤迄今,沒發現腫瘤復發或頸部轉移的情形。

並列摘要


Large cell undifferentiated carcinoma is a rare malignant neoplasms of the parotid gland. Final diagnosis is according to the histopathological features of this tumor, and a primary location of the lung should be ruled out. Surgery is the main treatment modality and postoperative radiotherapy is needed. The prognosis seems to be poor. A 66-year-old woman presented with a right infra-auricular mass in January, 2008. Head and neck computed tomography revealed a high-dense parotid mass with several satellite lymph nodes. Radical parotidectomy was performed and immunohistochemistry revealed large cell undifferentiated carcinoma. Postoperative radiotherapy was performed and no recurrence of tumor or neck metastasis was found. We review herein the clinicopathologic features, histopathology, treatment and prognosis.

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