TBT (Tributyltin) Toxicity to the Visual and Olfactory Functions of Tigerperch (Terapon jarbua Forsskål)

三丁基錫(Tributyltin, TBT)對花身雞魚(Terapon jarbua Forsskål)視覺及嗅覺功能之毒性作用

王達益(Dar-Yi Wang) ； 黃寶貴(Bao-Quey Huang)

《Zoological Studies》 38卷2期 (1999/04) Pp. 189-195

摘要

In order to understand tributyltin (TBT) toxicity to peripheral sensory functions, changes of visual and olfactory structures of tigerperch (Terapon jarbua Forsskål) were examined in juvenile and adult fish after exposure to 10, 50, and 100 μg TBT/l in juveniles and to 1 and 5 μg TBT/l in adults, respectively, for 7 d. Severe sloughing of squamous epithelial cells led to a thinning of the corneal epithelium. The retinomotor response of pigmented epithelium significantly decreased from 75.33% ± 2.88% (in the control group) to 63.33% ± 4.04% (p＜0.05, n=3) in the 100 μg/l group. The separation and necrotic corneal epithelium may lead to partial opacity and/or irregular abrasion and thus decrease retinomotor responses. In addition, scanning electron microscopic studies revealed edema, deformity, and sloughing of the microvilli, cilia, and rods in receptor cells of the olfactory epithelium. Electroolfactogram (EOG) responses significantly decreased from 3.0 ± 0.6 mV to 1.3 ± 0.5 mV (1 μg/l) and −0.4 ± 0.1 (5 μg/l), respectively (n=3).

關鍵字

三丁基錫 ； 抗附著劑 ； 角膜及嗅上皮 ； 黑色素移動反應 ； 味覺電位記錄(EOG)

並列摘要

In order to understand tributyltin (TBT) toxicity to peripheral sensory functions, changes of visual and olfactory structures of tigerperch (Terapon jarbua Forsskål) were examined in juvenile and adult fish after exposure to 10, 50, and 100 μg TBT/l in juveniles and to 1 and 5 μg TBT/l in adults, respectively, for 7 d. Severe sloughing of squamous epithelial cells led to a thinning of the corneal epithelium. The retinomotor response of pigmented epithelium significantly decreased from 75.33% ± 2.88% (in the control group) to 63.33% ± 4.04% (p＜0.05, n=3) in the 100 μg/l group. The separation and necrotic corneal epithelium may lead to partial opacity and/or irregular abrasion and thus decrease retinomotor responses. In addition, scanning electron microscopic studies revealed edema, deformity, and sloughing of the microvilli, cilia, and rods in receptor cells of the olfactory epithelium. Electroolfactogram (EOG) responses significantly decreased from 3.0 ± 0.6 mV to 1.3 ± 0.5 mV (1 μg/l) and −0.4 ± 0.1 (5 μg/l), respectively (n=3).

並列關鍵字

Tributyltin ； Corneal and olfactory epithelium ； Retinomotor response ； Electroolfactogram ； EOG