肺動脈高血壓定義為休息狀態下肺動脈收縮壓超過30毫米汞柱,平均肺動脈壓超過25毫米汞柱;或在運動狀態下肺動脈收縮壓超過35毫米汞柱,平均肺動脈壓超過30毫米汞柱。原發性肺動脈高血壓定義為無任何次發性原因之肺動脈高血壓。根據文獻記載,約有30-49%原先被診斷為原發性肺動脈高血壓的病患合併有自體免疫性甲狀腺疾病。如果未經發覺及適當的治療,日後將會惡化成右心衰竭;若給與適當的治療,肺動脈高血壓將可獲得改善。這裡,我們報導一位53歲重度肺動脈高血壓的病患合併有自體免疫性甲狀腺疾病。在經過確認及治療甲狀腺機能亢進後,右心衰竭症狀消失,肺動脈高血壓也獲得改善。
Hyperthyroidism affects the cardiovascular system in many ways including increased heart rate, cardiac arrhythmias, impaired diastolic function and increased systolic blood pressure. We report a case of severe pulmonary hypertension and right heart failure with no identifiable cause other than hyperthyroidism. After recognition and treatment of hyperthyroidism, the patient had prompt hemodynamic and symptomatic recovery.