- 期刊
Tracheobronchopathia Osteochondroplastica: A Report of Two Cases
氣管支氣管的骨軟骨病變：兩例病例報告
摘要
氣管支氣管的骨軟骨病變是一種罕見而且常是良性的一種疾病。最常發生的部位是在氣管，但有時也會影響到支氣管。我們現在報告兩例病例：一位是47歲的男性，主訴為長時間的間段性咳血；另一位是71歲女性，症狀是長期的乾咳和痰中帶血絲。氣管鏡檢查發現：第一個病人沿著氣管的前外側壁，有許多顆堅硬的疣狀突起，在第二個病人身上相同的突起更延伸到右側主支氣管內。病理報告證實是氣管支氣管的骨軟骨病變。第二個病患在4年後的氣管鏡追蹤下顯示，並無進一部變化。 氣管支氣管的骨軟骨病變其病因和發病原理目前仍然不是很清楚。它的嚴重度可從毫無症狀到嚴重的氣喘、咳血、和肺炎。一般來說，治療的方向主要為症狀處理。而它的鑑別診斷包括：澱粉樣變性病、氣管內類肉瘤病、結核病鈣化、乳頭狀瘤病、氣管支氣管鈣化症、及腫瘤。即早明白這一種病變，可以避免不必要的外科手術和化學治療。
並列摘要
Tracheobronchopathia osteochondroplastica (TO) is a rare and usually benign disorder affecting the trachea, and occasionally the bronchi. We describe two cases of TO: one, a 47 y/o man with long-term intermittent hemoptysis, and the other, a 71 y/o woman with the symptoms of cough with occasional hemoptysis. Bronchoscopy revealed multiple papilla-like nodules along the anterolateral wall of the trachea in both patients, which extended to the right main bronchus in the latter patient. Pathologic examination confirmed the diagnosis of TO. Bronchoscopic examination revealed no changes after 4 years in the latter case The etiology and pathogenesis of TO are unknown. The severity of TO ranges from no symptoms to severe dyspnea, hemoptysis, or pneumonitis. Treatment is seldom necessary. The differential diagnosis of nodular lesions includes amyloidosis, endobronchial sarcoidosis, calcified lesions of tuberculosis, papillomatosis, tracheobronchial calcinosis, and neoplasms. Awareness of this condition is important so as to avoid unnecessary surgery or chemotherapy