Malignant Melanoma Presenting as a Mediastinal Mass: A Case Report

惡性黑色素瘤以縱膈腔腫瘤形式表現：病例報告

呂紹煒(Shaw-Wei Leu) ； 李錦輝(Kam-Fai Lee) ； 林博彥(Paul Y. Lin) ； 楊政達(Cheng-Ta Yang)

《胸腔醫學》 22卷1期 (2007/02) Pp. 73-78

https://doi.org/10.29806/TM.200702.0011

摘要

原發性縱膈腔惡性黑色素瘤極為少見；診斷以病理切片顯示表皮樣細胞其細胞質內含有黑色素及典型的免疫組織化學染色表現為主；以及臨床上須排除其他原發病灶。臨床症狀包括咳嗽、胸痛、氣促、咳血、吞嚥困難及體重減輕。一般預後不佳，亦無公認的最適治療。在此我們報告一位49歲女性以縱膈腔腫瘤為其惡性黑色素瘤的最初表現。

關鍵字

縱膈腔腫瘤 ； 惡性黑色素瘤

並列摘要

Primary mediastinal melanoma is extremely rare. The diagnosis is based on the presence of epithelioid cells with cytoplasmic melanin pigment in the histological study and a typical expression in immunohistochemical studies, and the exclusion of other primary sites of tumor. Clinical symptoms include cough, chest pain, shortness of breath, hemoptysis, dysphagia, and weight loss. The prognosis is usually unfavorable and there is no agreement on optimal therapy. Herein, we report a 49-year-old female patient with malignant melanoma presenting as a mediastinal mass without an extrathoracic primary.

並列關鍵字

mediastinal mass ； malignant melanoma