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Mediastinal Parathyroid Adenoma: Report of a Case Treated Successfully by Video-Assisted Thoracoscopic Surgery

縱膈腔副甲狀腺腺瘤-成功以胸腔鏡手術治療之病例報告

摘要


縱膈腔異位性副甲狀腺腺瘤是一種罕見的縱膈腔腫瘤,臨床上通常以高血鈣症及副甲狀腺素過高來表現,治療以手術切除為主。在此一病例報告中,我們呈現一位71歲女性病患因全身無力及意識昏迷至醫院就診,實驗室檢查發現有原發性副甲狀腺機能亢進的現象,副甲狀腺核醫掃瞄及胸腔電腦斷層顯現前縱膈腔有一功能亢進之病灶。病患接受胸腔鏡手術摘除此一病灶,病理檢查報告為一副甲狀腺腺瘤。病患術後恢復良好,在術後1個月及6個月追蹤並無發現高血鈣之情形。除了報告此一罕見病例外,我們也回顧縱膈腔副甲狀腺腺瘤的治療方式。

並列摘要


Herein, we report a rare case of mediastinal ectopic parathyroid adenoma successfully treated by video-assisted thoracoscopic surgery (VATS). A 71-year-old female initially presented with general weakness and consciousness change. Biochemical examination revealed hypercalcemia and an elevated intact parathyroid hormone (i-PTH) level. 99mTc-sestamibi (MIBI) scintigraphy revealed an ectopic parathyroid gland in the anterior mediastinum. Chest computed tomography (CT) scan revealed a relatively well-defined soft tissue mass at the right anterior mediastinum, that was successfully treated with a videoassisted thoracoscopic surgerical approach. The postoperative course was uneventful, and her serum calcium and i-PTH levels returned to a normal range after operation. The pathologic report confirmed ectopic parathyroid adenoma. We report this case with a review of the literature.

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