- 期刊
Pulmonary Melioidosis Associated with Organizing Pneumonia: A Case Report
類鼻疽桿菌肺炎併器質化肺炎：案例報告
摘要
Melioidosis is a tropical infectious disease caused by Burkholderia pseudomallei, which affects the lungs most frequently. Organizing pneumonia (OP) can be cryptogenic or secondary to lung infections, and is rarely associated with melioidosis. We report the case of a 64-year-old male patient who presented with solitary pulmonary opacity that progressed to fulminant septicemia under treatment with empiric antibiotics and oral steroid. The pathology report showed organizing pneumonia, and B. pseudomallei was isolated from the blood. The patient recovered very well after treatment was shifted to imipenem/cilastatin plus sulfamethoxazole-trimethoprim.
並列摘要
類鼻疽（Melioidosis）為感染類鼻疽桿菌Burkholderia pseudomallei所引起的熱帶地域感染疾病，肺部是最常被影響的器官。器質化肺炎（organizing pneumonia）是肺臟針對許多不同病因所造成急性損害的一種修護反應。本文分享一個病例，初始表現為單一肺斑塊，先以抗生素Amoxicillin-clavulanate作為肺炎治療。單一肺斑塊病理切片報告器質化肺炎，加上口服類固醇治療後，病情惡化為敗血性休克併急性呼吸衰竭。經過加護病房照顧及抗生素Imipenem／cilastatin加上Sulfamethoxazole-trimethoprim使用，感染獲得控制，病人最後穩定出院。
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