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Pre-operative Low Dose Radiotherapy of Rectal Cancer with Fournier's Gangrene

直腸癌病患併發福尼耳壞疽術前低劑量放射治療:一病例報告及文獻回顧

摘要


福尼耳壞疽在直腸癌病患很少見卻經常致命。我們報告一位酗酒之男性病患,他罹患至少是腫瘤第三期之直腸癌及福尼耳壞疽。我們安排了腫瘤切除前之低劑量放療,而不是依照有些文獻上所主張,要把放療整個療程延後到傷口穩定癒合後再開始。就算放療主要之治療劑量應在腫瘤切除後再施予,我們相信術前低劑量之放療對幫助病患腫瘤之切除和臨床整體結果有正面效益。這篇文章同時也回顧了文獻上有關同時有直腸癌併發福尼耳壞疽之病例,並對放療之時機作一討論。

並列摘要


Fournier's gangrene is a rare but often fatal manifestation of rectal cancer. We report a case of at least T3 stage adenocarcinoma of rectum with Fournier's gangrene in a male alcoholic abuser. Instead of postponing radiation therapy as suggested by some literature, we arranged low dose pre-operative radiation therapy and found the following operation was smoother than expected. Whereas full dose radiation therapy of the cancer should be performed after resection as suggested by the literature, we believe pre-operative low-dose radiation therapy may help the execution of tumor resection and thus the general outcome of the patient. This report also summarizes a review of the literature on the management of de novo Fournier掇 gangrene cases with rectal cancers and discusses the role and timing of radiation therapy in such cases.

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