Fournier's gangrene is a rare but often fatal manifestation of rectal cancer. We report a case of at least T3 stage adenocarcinoma of rectum with Fournier's gangrene in a male alcoholic abuser. Instead of postponing radiation therapy as suggested by some literature, we arranged low dose pre-operative radiation therapy and found the following operation was smoother than expected. Whereas full dose radiation therapy of the cancer should be performed after resection as suggested by the literature, we believe pre-operative low-dose radiation therapy may help the execution of tumor resection and thus the general outcome of the patient. This report also summarizes a review of the literature on the management of de novo Fournier掇 gangrene cases with rectal cancers and discusses the role and timing of radiation therapy in such cases.