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A CASE OF HEPATOCELLULAR CARCINOMA WITH TUMOR THROMBUS EXTENDING FROM THE INFERIOR VENA CAVA TOWARDS THE RIGHT ATRIUM SHOWS COMPLETE RESPONSE AFTER COMBINED TREATMENT WITH RADIATION THERAPY AND SORAFENIB

以放射線及標靶藥物Sorafenib治療肝癌合併下腔靜脈及右心房腫瘤栓塞並達到完全緩解效果的一個案例報告

摘要


本文報告一肝癌患者因合併下腔靜脈及右心房腫瘤栓塞而接受放射線治療。這名55歲C型肝炎患者,於確診肝癌時即發現同時合併下腔靜脈及右心房腫瘤栓塞。病人接受放射線治療,總劑量35Gy分15次,同時服用標靶藥物Sorafenib。後續影像追蹤發現腫瘤栓塞達到完全緩解效果。

並列摘要


We report a case of advanced hepatocellular carcinoma (HCC) with tumor thrombosis extending from the inferior vena cava (IVC) towards the right atrium (RA) treated by radiation therapy (RT) and targeted therapy with sorafenib. A 55-year old man who had been a hepatitis C carrier eventually developed liver cirrhosis and primary HCC. Tumor thrombosis spanning across the IVC and the RA was noted at initial diagnosis. He received RT with 37.5 Gy in 15 fractions in addition to concurrent and sequential sorafenib therapy. Follow-up imaging studies showed complete response of IVC and RA thrombus.

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