- 期刊
台灣冬季西部養豬場勞工豬流感病毒抗體之調查
Serological Survey of Swine Influenza Virus on Pig Farm Workers in Winter in Western Taiwan
摘要
Several plagues occur in animal husbandry in Taiwan every year. Workers in animal houses exposed to those infectious agents may become ill through zoonoses. Since Hong Kong's outbreak of the HPAI subtype H5N1 in 1997, many workers have been threatened by Influenza viruses. This preliminary surveillance program was established for the workers that winter. To evaluate the exposure and prevalence rate of the work-related zoonic Influenza, a field study, including a questionnaire containing disease history, self syndromes, and personal hygiene status, was conducted. Influenza H1N1 swine subtype virus was used as the test strain. Exposure conditions were evaluated by serum titers and the carrier state of workers was determined by oral swabs. The subjects consisted of two hundred workers, 152 in the exposed group, and 48 in the non-exposed group. The questionnaires show that over 80% of the subjects had physical contact with swine excretions in the exposed group and that many flu-related syndromes were work related. From the blood samples, the specific antibody for swine influenza was found in 27.5% (55) of the workers, with a significantly higher prevalence in the exposed group (p＜0.01). Based on an RT-PCR test using two primers of the swine Influenza virus, none of the workers were confirmed to be in the carrier state. Furthermore, based on the statistical relationships of the presence of specific antibodies with occupational exposure and personal hygiene habitats, significant correlations were found between workplace, eating in the workplace, and needle stick and the pig flu disease, but the correlations with other pet diseases were not significant. Otherwise, influenza-related disease and symptoms were strongly associated with the type of work performed. A significantly higher rate of antibodies was observed in 40% (8) of workers who had severe flu syndromes than in the 26.1% (45) who did not (p＜0.01). We conclude that the pig-farm workers have been exposed to the Influenza H1N1 swine subtype virus, and some of them may be infected.
並列摘要
Several plagues occur in animal husbandry in Taiwan every year. Workers in animal houses exposed to those infectious agents may become ill through zoonoses. Since Hong Kong's outbreak of the HPAI subtype H5N1 in 1997, many workers have been threatened by Influenza viruses. This preliminary surveillance program was established for the workers that winter. To evaluate the exposure and prevalence rate of the work-related zoonic Influenza, a field study, including a questionnaire containing disease history, self syndromes, and personal hygiene status, was conducted. Influenza H1N1 swine subtype virus was used as the test strain. Exposure conditions were evaluated by serum titers and the carrier state of workers was determined by oral swabs. The subjects consisted of two hundred workers, 152 in the exposed group, and 48 in the non-exposed group. The questionnaires show that over 80% of the subjects had physical contact with swine excretions in the exposed group and that many flu-related syndromes were work related. From the blood samples, the specific antibody for swine influenza was found in 27.5% (55) of the workers, with a significantly higher prevalence in the exposed group (p＜0.01). Based on an RT-PCR test using two primers of the swine Influenza virus, none of the workers were confirmed to be in the carrier state. Furthermore, based on the statistical relationships of the presence of specific antibodies with occupational exposure and personal hygiene habitats, significant correlations were found between workplace, eating in the workplace, and needle stick and the pig flu disease, but the correlations with other pet diseases were not significant. Otherwise, influenza-related disease and symptoms were strongly associated with the type of work performed. A significantly higher rate of antibodies was observed in 40% (8) of workers who had severe flu syndromes than in the 26.1% (45) who did not (p＜0.01). We conclude that the pig-farm workers have been exposed to the Influenza H1N1 swine subtype virus, and some of them may be infected.
參考文獻
延伸閱讀
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