An Algorithm for Use of Acticoat Dressing in Acute Burns and Exfoliative Diseases

Acticoat (Smith and Nephew)是一種含銀的三層敷料，它能釋放出奈米結晶銀，產生出一種快速而穩定的殺菌活性。從2005年五月到2006年三月，我們共收集26位病患，其中16位是急性燒燙傷病患，8位是大面積表皮壞死剝落傷口病患。平均傷口佔體表面積33.8%。Acticoat治療面積覆蓋19.4%的體表面積。平均治療天數是10.1天。傷口癒合面積佔Acticoat覆蓋治療面積的91%。有兩名病患因為敷料的掉落位移，需在治療中途更換部分敷料。一名病患在治療後，仍有陽性的細菌培養結果。經由本研究得知，Acticoat有穩定的殺菌效果，能長時間使用，降低更換敷料的次數，及降低在更換敷料時所造成的皮膚傷害和病患的疼痛。根據我們的研究，我們訂定了Acticoat應用於急性燒燙傷及大面積表皮壞死剝落疾病之流程。

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並列摘要

Acticoat (Smith and Nephew) is a three-layer dressing, consisting of an inner rayon/polyester absorptive core between two layers of silver-coated, high-density polyethylene mesh. Silver is released as a nanocrystalline form when it is in a moist environment. It has a rapid and sustained bactericidal activity. Between May 2005 and March 2006, 26 patients were included in this study: 18 were patients with acute burn injuries, 8 were patients with exfoliative disease, such as Steven-Johnson Syndrome and Toxic epidermal necrolysis. The involved areas had a mean of 33.8% total body surface area. The areas which covered with Acticoat had a mean of 19.4% total body surface area. The mean duration of treatment was 10.1 days. The mean healing percentage of the wounds was 91% of the total treatment areas. The dressings in two cases needed to be replaced partially during treatment due to partial dislodgement. Only one patient had positive wound culture after the treatment. In this study, Acticoat demonstrated sustained bactericidal properties, long application time, and reducing trauma with pain during application. We also proposed an algorithm for using Acticoat dressings in acute burns and exfoliative diseases.

並列關鍵字

Acticoat ； burns ； exfoliative disease TEN toxic epidermal necrolysis SJS Steven-Johnson syndrome

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An Algorithm for Use of Acticoat Dressing in Acute Burns and Exfoliative Diseases

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