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An Unusual Presentation of Dextran Related Anaphylactic Reaction

一個與使用葡萄聚糖(Dextran)有關的罕見過敏反應-病例報告

摘要


葡萄聚糖(Dextran)經常被使用在顯微手術術後照顧,曾有零星報告葡萄聚糖所引起的肺水腫。而今我們將報告一例由葡萄聚糖所引起的非心因性肺水腫,且該過敏反應之以高血壓表現亦屬罕見之呈現方式。 一個29歲男性於兩年前接受四隻手指顯微植回手術,本次則接受前側股游離皮瓣手術以覆蓋疤痕解離後的皮膚缺損。術中術後使用葡萄聚糖,初期呈現高血壓與後期肺水腫、血小板低下,於停用葡萄聚糖後血壓迅速回到術前水平,且在呼吸器支持療法下三天後呼吸狀況恢復正常。 該病患於兩年前顯微手術後亦曾接受葡萄聚糖的施予,故本次應屬過敏反應無誤。本文中亦回顧諸多文獻,並探討其可能的作用機轉。

關鍵字

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並列摘要


Dextran is frequently used following microsurgical free tissue transfer and replantation. The incidence of dextran induced pulmonary edema has been reported sporadically. We report here a case of dextran induced non cardiogenic pulmonary edema having a late presentation. The rare presentation of an anaphylactic reaction presenting with hypertension is also discussed.

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