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Assessment of central motor conduction time in patients with cervical spondylotic myelopathy

頸椎關節脊髓病變之中樞運動神經傳導時間檢查

摘要


Motor evoked potential (MEP) study by transcranial electric or magnetic stimulation or the motor cortex has been practically used for clinical evaluation of electrophysiological function of the central motor pathway. By using a percutaneous magnetic stimulation over the motor cortex and F-wave measurement from the median nerve stimulation, central motor conduction time (CMCT) from motor cortex to C8 spinal cord was measured in 25 patients with cervical spondylotic myelopathy (CSM) and in 16 healthy subjects. Latencies from motor cortex to C8 spinal cord was 10.4±2.1 (mean ±ISD) ms which was significantly longer than 5.3±0.8 ms in controls under the correction for body height (covariance, p<0.01). The amplitude of MEP obtained in recording muscle of abductor pollicis brevis was 3.2±1.3 mV in patients with CSM. which was statistically lower than the result of6.7±2.1 mV in controls (p<0.001). This non-invasive indirect method is objective, measurable and can provide valuable electrophysiological data in the assessment of motor function in patients with CSM.

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並列摘要


Motor evoked potential (MEP) study by transcranial electric or magnetic stimulation or the motor cortex has been practically used for clinical evaluation of electrophysiological function of the central motor pathway. By using a percutaneous magnetic stimulation over the motor cortex and F-wave measurement from the median nerve stimulation, central motor conduction time (CMCT) from motor cortex to C8 spinal cord was measured in 25 patients with cervical spondylotic myelopathy (CSM) and in 16 healthy subjects. Latencies from motor cortex to C8 spinal cord was 10.4±2.1 (mean ±ISD) ms which was significantly longer than 5.3±0.8 ms in controls under the correction for body height (covariance, p<0.01). The amplitude of MEP obtained in recording muscle of abductor pollicis brevis was 3.2±1.3 mV in patients with CSM. which was statistically lower than the result of6.7±2.1 mV in controls (p<0.001). This non-invasive indirect method is objective, measurable and can provide valuable electrophysiological data in the assessment of motor function in patients with CSM.

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