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以流程模式建立觀點探討生物路徑的知識表示法

Knowledge Representation of Biological Pathways from a Process Modeling Perspective

摘要


要更加了解人體中各種不同的生物機制間的複雜鏈結網路,一個有關生物路徑的基礎知識就必須先被建立起來。本研究提出並討論一個以流程規劃為基礎的知識表示法在生物路徑的應用。本研究首先介紹此知識表示法的高階的模型建立概念,而復詳細說明如何應用此知識表示法來表示一個生物路程。從本研究的結果可知,此知識表示法雖然十分簡單,卻足以代表任何型態的生物路徑。

並列摘要


To better understand the internetworking of different biological mechanisms working in a human body, it is essential to first establish a fundamental knowledge of the biological pathways. In this paper, a knowledge representation scheme for biological pathways is presented and discussed. First, the high level modeling concepts involved in this scheme are explained using a simple status-activity diagram. Detailed knowledge representation of a biological pathway is then investigated and discussed using a class-based approach. The proposed knowledge representation scheme is simple yet comprehensive enough to cover any types of biological pathways.

參考文獻


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