This research tracked the girls who studied in the class for math and science gifted students at six high schools for two years and in order to know the process of choosing to enter the foundation science department. Research findings showed that it was very complicated for these girls to choose entering the foundation science department. The factors which influence their choices were interests, abilities, important others, learning experience... etc. On the contrary, we could see the influences of the need of the employment market and the social values on the students who didn’t want to enter the foundation science department. They were not sure the future development at grade eleven, but they had their own viewpoints at grade twelve. When they chose, they sometimes felt hesitant. But they felt determined when they set their goals. In addition, they also had some plans for the future learning. According to the above findings, there were some suggestions proposed for reader's reference.