具有易流血特質之單一類上皮型Spitz痣 –病例報告及文獻回顯–

Pure Epithelioid Spitz Nevus with Easily Bleeding Character -A Case Report & Literature Review-

蕭晨隆(Cheng-Lun Hsiao) ； 溫素瑩(Su-Ying Wen)

《中華皮膚科醫學雜誌》 18卷3期 (2000/09) Pp. 223-228

摘要

Spitz痣為一種罕見的良性皮膚腫瘤，組織病理學上可分為兩型，一型由梭狀細胞組成，另一型則由梭狀細胞與類上皮細胞混合而成，觀諸文獻，甚少有單一類上皮細胞形成之Spitz痣。本文報告一二十四歲男性，於右大腿外側出現一表面光滑具彈性之紅色結節，大小為0.8 × 0.8 × 0.5cm，有易流血之特質，並曾有一次較大量出血的經驗，臨床上看似化膿性肉芽腫，其組織病理顯示許多由單一類上皮細胞組成之細胞巢，細胞巢的大小由病灶淺部至深部依序遞減，這些類上皮細胞呈S-100蛋白質陽性反應，細胞巢間並有大量血管增生，為一罕見由單一類上皮細胞組成之Spitz痣。

並列摘要

Spitz nevus is a rare benign skin tumor. Histologically it may be classified as spindle cell nevus and mixed cell type of spindle and epithelioid cell. Pure epithelioid Spitz nevus is rare. A 21-year-old male had a 0.8 × 0.8 × 0.5cm smooth-surfaced, elastic, red-brownish, dome-shaped nodule over the lateral aspect of the right thigh and suffered from one episode of massive bleeding. Clinically it resembled a pyogenic granuloma. Histopathological examination of the lesion showed nests composed of pure epithelioid cells, which are S-100 positive. Massive vascular proliferation was also found. It was a rare Spitz nevus of pure epithelioid cells type.

並列關鍵字

pure epithelioid spitz nevus ； pyogenic granuloma ； vascular proliferation