- 期刊
兒童的丘疹性黃色瘤 –病例報告–
Papular Xanthoma in Children -A Case Report-
摘要
一位1歲7個月的小男孩，6個月大時在臉上出現許多無症狀黃棕色丘疹，一年來軀幹及四肢陸續出現相同病灶。皮膚切片有泡沫狀組織(foamy histiocytes)聚集在真皮部。染以PAS、CD34及S-100泡沫狀細胞呈陰性反應，而CD68、Sudan black B及Oil Red O染色均呈陽性反應。電子顯微鏡(EM)下可見泡沫狀細胞質內有脂質空胞及部分屁罍狀體(laminated bodies)，未發現有Birbeck氏顆粒。血中膽固醇及三酸甘油脂，均屬正常，腹部超音波及胸部X光檢查無特殊發現。依據臨床及病理特徵此病例診斷為丘疹性黃色瘤。
關鍵字
無資料並列摘要
A 1-year-7-month-old boy had several asympatomatic popular eruptions, particularly on the face, that initially developed at 6 months of age. Individual lesions were yellow to yellow-brownish. New lesions continued to develop over the trunk and limbs in one year. Skin biopsy showed aggregation of foamy histiocytes in the dermis. These cells were positive for CD68, but negative for CD34 and S-100 protein. Periodic acid-Schiff (PAS) stain was negative. Sudan black B and oil-O stains were positive on frozen section. The electron microscopic studies revealed that the foamy cells contain lipid vacuoles and some incomplete laminated bodies. Birbeck granule is absent. The serum levels of total cholesterol and triglyceride were within normal limits. Sonography of upper abdomen and chest X-ray showed no abnormal finding. Based on the clinical and laboratory findings, popular xanthoma was diagnosed.
延伸閱讀
- Wu, W. F., Hung, P. L., & Shih, J. S. (1980). 幼年性黃色肉芽腫瘤之一病例報告. Acta Paediatrica Sinica, 21(1), 30-33. https://www.airitilibrary.com/Article/Detail?DocID=00016578-198003-21-1-30-33-a
- 沈應誠、袁漢良（1996）。結膜惡性黑色素瘤－中國小孩之病例報告。中華民國眼科醫學會雜誌，35(3)，359-363。https://doi.org/10.30048/ACTASOS.199609.0017
- Young, W. N., Lin, C. Y., Hsu, C. H., & Hsu, H. C. (1984). 一過性新生兒膿疱性黑皮症之一例報告. Acta Paediatrica Sinica, 25(1), 60-63. https://www.airitilibrary.com/Article/Detail?DocID=00016578-198403-25-1-60-63-a
- Yang, Y. H., Tsai, M. J., Tsau, Y. K., Wang, L. H., Lin, Y. T., Liu, J. C., Lo, J. T., & Chiang, B. L. (1999). 兒童多形性紅斑之臨床觀察. Acta Paediatrica Sinica, 40(2), 107-111. https://doi.org/10.7097/APS.199904.0152
- （1999）。Xanthoma of Bone in Child。Acta Paediatrica Sinica，40(s_1)，53-54。https://doi.org/10.7097/APS.199904.0017