擬似血管瘤的氣脤細胞黑色素瘤－病例報告及文獻回顧－

Balloon Cell Melanoma Mimicking Hemangioma -A Case Report and the Literature Review-

侯源裕(Yuan-Yue Hou) ； 鄭詩宗(Shih-Tsung Cheng) ； 許晴哲(Roger Chin-Che Hsu) ； 陳國熏(Gwo-Shing Chen)

《中華皮膚科醫學雜誌》 21卷3期 (2003/09) Pp. 280-285

https://doi.org/10.29784/DS.200309.0007

摘要

氣脤細胞黑 瘤是極為罕見的黑色素瘤變異型。病灶常未見黑色素沉積，病理下空
泡化的細胞常讓人誤認為良性。欲診斷為氣脤細胞黑色素瘤，其氣脤細胞化細胞須達50%
以上。本病例為男性，其右手有一肉色丘疹，後來開始有不尋常的紅棕色丘疹節結樣的變
化。門診臨床診斷及病理科診斷為血管瘤，但是病理可見明顯的氣脤細胞。免疫組織化學
特殊染色S-100、HMB-45均呈現陽性反應。deltopectoral區及腋下淋巴結切除發現轉拸。
最後證實是氣脤細胞黑色素瘤合併淋巴結轉移。病人接受手術切除、淋巴結切除及三次化
學治療療程，在隨後二年的追蹤並無復發或轉移。回顧過去文獻報告，氣脤細胞黑色素瘤腫
瘤的預後及轉移性與其他黑色素瘤並無不同。(中華皮誌21:280-285, 2003)

並列摘要

Balloon cell melanoma is a rare histological variant of all melanoma. Histopathological interpre-
tation of this tumor could be difficult, especially when the lesions contain little or no pigment. In order
to diagnose balloon cell melanoma the foamy cells have to constitute more than 50% of tumor cells.
Herein. We report a male whose lesion first appeared as a banal papule on the right hand , then evolved
into some uncanny violaceous-brownish noduloplaques. Initial clinical and athological diagnosis was
hemangioma; however, the prominent foamy cells were noticed. Special stains disclosed positive reac-
tivity with HMB-45 and S-100. The deltopectoral and axillary lymph nodes dissection verified lymph
node metastases. The final diagnosis is ballon cell melanoma with lymph nodes metastases. Alter
surgical excision, lymph nodes dissection and two courses of chemotherapy, the patient is alive and
free of disease 2 years after diagnosis. A review of literature comparing the prognostic significance or
metastatic propensity of ballon cell melanoma with other more common types of melanoma revealed
no significant difference. (Dermatol Sinica 21:280-285, 2003)

並列關鍵字

Melanoma, Balloon cell, Prognosis