並列摘要
The continuous threat of influenza is due to imperfect vaccines and widespread resistance to existing antivirals. This problem is particularly acute during a pandemic. It determines the urgency and necessity to develop safe and effective vaccines against divergent influenza viruses. This article describes the concept and development of universal influenza vaccine based on the relatively conserved sequences of M2e, HA and other proteins of influenza virus. Several research results were summarized briefly to demonstrate the possibility and potential of such universal vaccines.
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