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Priapism after Long-acting Risperidone Injection

長效Risperidone注射後的陰莖異常勃起

摘要


目標︰陰莖異常勃起是沒有性刺激而發生的持續的、疼痛的勃起狀態。它被報告與許多抗精神病藥物的使用有關,包括clozapine,olanzapine和risperidone,但長效risperidone注射尚未被報告有這樣的副作用,在這裡我們報告一位使用長效risperidone注射後產生這樣副作用的個案。個案報告:一位27歲男性,罹患妄想型精神分裂症已經十年,在使用長效risperidone注射兩週後,產生陰莖異常勃起。在治療後,個案於接下來六個月的追蹤中,否認有任何勃起障礙及再次陰莖異常勃起。結論:因抗精神病藥物治療所造成的陰莖異常勃起是非常少見。當臨床醫師處方這類藥物時,無論如何都必需瞭解此類併發症發生的可能性。

並列摘要


Objective: Priapism is a persistent, painful erection that occurs without sexual stimulation. It has been associated with the use of many antipsychotic agents, including clozapine, olanzapine and risperidone but has not been reported as a side effect of long-acting risperidone injection. Here we report a case of this adverse event in a patient treated with long-acting risperidone. Case report: A 27-yearold man with a 10-year history of paranoid-type schizophrenia developed priapism two weeks after a long-acting risperidone injection. After treatment, he denied any erectile abnormalities and had had no subsequent episodes of priapism during 6 months of follow up. Conclusion: Priapism rarely results from treatment with antipsychotic agents. Clinicians, however, must be aware of the possibility of this complication when prescribing these drugs.

參考文獻


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