Psychopharmacoepidemiology: Scope and Application

精神藥物流行病學的研究範疇與應用

張明永(Mian-Yoon Chong)

《台灣精神醫學》 22卷1期 (2008/03) Pp. 3-15

https://doi.org/10.29478/TJP.200803.0002

摘要

藥物治療是目前最常醫療處置，尤其是精神科的治療。超過一半以上的藥物嚴重副作用是在核准上市後被發現的；因此，為了確保藥物的安全性，藥物上市後的研究尤其來的重要。透過精神藥物流行病學，可以有效的對上市後之抗精神藥物的監控及其風險與效益的研究，探討抗精神藥物是如何的處方、應用、以及影響其處方及預後的種種因素。本綜說簡介精神藥物流行病學的發展，特別是研究的範疇、限制、應用與將來的展望。

關鍵字

精神藥物流行病學 ； 藥物流行病學 ； 處方行為 ； 藥物使用概況

並列摘要

The most common therapeutic intervention in medicine is the writing of a prescription. It is especially true in psychiatry as pharmacotherapy has become its mainstay treatment. With over half of the approved drugs having serious adverse effects that were not detected before the approval, it is therefore important to study post-marketing drugs in order to ensure the safety of a drug. The benefits and risks of a psychotropic drug could be studied through using psycho pharmaco epidemiological methods, a science underlying post-marketing drug surveillance. It delineates how psychotropic drugs are prescribed and utilized, investigates reasons underlying prescriptions, and assesses outcomes and variables which may affect these outcomes. This review covers the introduction and development of psycho pharmaco epidemiology, specifically to its scope and limitation, examples of studies published in the past years, and its future perspectives.

並列關鍵字

Psychopharmacoepidemiology ； pharmacoepidemiology of psychotropic drugs ； prescribing behavior ； drug utilization

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