Weight Management Program for Overweight Patients with Schizophrenia: A 12-week Randomized Controlled Trial

體重控制計畫應用在體重過重之精神分裂症患者：十二週隨機對照臨床試驗

黃斯聖(Si-Sheng Huang) ； 邱南英(Nan-Ying Chiu)

《台灣精神醫學》 22卷1期 (2008/03) Pp. 67-73

https://doi.org/10.29478/TJP.200803.0008

摘要

Objective: To evaluate the effectiveness of a weight-management program for overweight schizophrenics. Methods: The patients were recruited from both the outpatient clinic and the psychiatric day hospital. They were randomly assigned to an intervention group (n=14) or control group (n=14). Values for body weight, body-mass index, and body fat were measured. We assessed psychiatric symptoms with the Clinical Global Impression-Severity and Brief Psychiatric Rating Scale. We used the two-tailed paired t-test to evaluate within-group changes. Between-group differences were assessed using univariate analysis of variance. Results: There was no significant change in body weight of the patients from baseline to endpoint for either group. The severity of psychiatric symptoms in the intervention group was decreased significantly (CGI-S:t=2.280, df=13, p=.040; BPRS: t=5.362, df=13, p＜.001). Conclusion: The body weight of the overweight schizophrenics did not decrease by this program, however, their psychiatric symptoms were improved by it. The results need to be duplicaled in future studies.

關鍵字

體重控制 ； 體重過重 ； 精神分裂症 ； 精神症狀

並列摘要

Objective: To evaluate the effectiveness of a weight-management program for overweight schizophrenics. Methods: The patients were recruited from both the outpatient clinic and the psychiatric day hospital. They were randomly assigned to an intervention group (n=14) or control group (n=14). Values for body weight, body-mass index, and body fat were measured. We assessed psychiatric symptoms with the Clinical Global Impression-Severity and Brief Psychiatric Rating Scale. We used the two-tailed paired t-test to evaluate within-group changes. Between-group differences were assessed using univariate analysis of variance. Results: There was no significant change in body weight of the patients from baseline to endpoint for either group. The severity of psychiatric symptoms in the intervention group was decreased significantly (CGI-S:t=2.280, df=13, p=.040; BPRS: t=5.362, df=13, p＜.001). Conclusion: The body weight of the overweight schizophrenics did not decrease by this program, however, their psychiatric symptoms were improved by it. The results need to be duplicaled in future studies.

並列關鍵字

weight management ； overweight ； schizophrenia ； psychiatric symptom

參考文獻

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Kwon JS,Choi JS,Bahk WM(2006).Weight management program for treatment-emergent weight gain in olanzapine-treated patients with schizophrenia or schizoaffective disorder: A 12- week randomized controlled clinical trial.J Clin Psychiatry.67,547-553.

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