Leukopenia Induced by Quetiapine in a Patient with History of Clozapine-induced Leukopenia

Quetiapine引發白血球減少症於曾有Clozapine 引起之白血球減少症病史之病患

王智仁(Chih-Jen Wang) ； 張正辰(Cheng-Chen Chang) ； 黃斯聖(Si-Sheng Huang)

《台灣精神醫學》 25卷3期 (2011/09) Pp. 191-194

https://doi.org/10.29478/TJP.201109.0008

並列摘要

Objective: Many antipsychotic medications can cause hematological abnormalities. Quetiapine is a dibenzothiazepine derivative similar to clozapine, an antipsychotic agent which has the highest risk of causing blood dyscrasias. A case of quetiapine-induced leukopenia is described here in a patient who had a previous history of leukopenia induced by clozapine. Case Report: A 34-year-old Taiwanese woman patient with schizophrenia had a history of clozapine-induced leukopenia. She developed leukopenia again after her receiving quetiapine treatment. After quetiapine was discontinued, her white blood count was increased to a normal range. Conclusion: Physicians should be cautious of having potential hematological abnormalities before prescribing leukopenia-causing drugs, especially in patients with a history of drug-induced leukopenia.

並列關鍵字

clozapine ； quetiapine ； leukopenia ； blood dyscrasia

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