The aim was to determine the methodological quality (MQ) of therapy research articles published in four representative ISI dental journals. MQ was measured using the MINCIR scale and level of evidence (LoE) using the Oxford Center for Evidence Based Medicine ranking. MINCIR general score was 12.84 ± 6.08, the difference between journals scores was statistical significant (p=0,0001). The LoE were: 4 for 59.6%, 3b for 3.0%, 2b for 21.2%, and 1b for 16.2% of articles, being this difference statistical significant (p = 0,003). MQ and LoE for dental therapy research is low. Higher impact factor journals not necessarily publish the higher quality research.