北高雄地區幽門螺旋桿菌感染與消化性潰瘍之現狀

Current Status of H. Pyloric Infection and Peptic Ulcer in North Kaohsiung Area

彭道雄(Daw-Shyong Perng) ； 蔡定洲(Ting-Chou Tsai) ； 蔣振疆(Chen-Chiang Chiang) ； 王志文(Chu-Wen Wang) ； 王正信(Jeng-Shing Wang)

《秀傳醫學雜誌》 9卷3&4期 (2009/12) Pp. 95-100

摘要

Objectives: H. pylori infection plays an important role in the pathogenesis of peptic ulcers. We want to know current status of H. pylori infection and peptic ulcer in the northern Kaohsiung area.
Methods: We analysed clinical records and questionnaires retrospectively of 164 outpatients (male: 86; female: 78) at E-Da Hospital. The patients suffered from peptic ulcers proven by both endoscopy and CLO test.
Results: H. pylori infection rates of gastric ulcer, duodenal ulcer, and gastric ulcer complicated with duodenal ulcer were 43.69%, 53.19%, and 63.64%, respectively (p＜0.05). In addition, the relative ratios of male to female patients with positive tests were 1.25, 1.5, and 1.1, respectively. Among gastric ulcer patients, those with blood-type O suffered more from H. pylori infection (p＜0.05). However, among duodenal ulcer patients, those with blood-type B suffered more from H. pylori infection (p＜0.05). Among gastric and duodenal ulcer patients, those of Hakka ethnicity suffered more from H. pylori infection (p＜0.05). Among gastric and duodenal ulcer patients, there was no correlation between H. pylori infection and smoking, drinking tea, or non-steroid anti-inflammatory drug usage. However, there was a correlation between H. pylori infection and coffee usage (p＜0.05).
Conclusions: Due to specific geographic and cultural conditions, there could be distinctive presentations of peptic ulcers in the north Kaohsiung area. Better understanding of peptic ulcer status in this part of our country could be meaningful for better preventive medicine.

關鍵字

血型 ； 幽門螺旋桿菌感染 ； 消化潰瘍

並列摘要

Objectives: H. pylori infection plays an important role in the pathogenesis of peptic ulcers. We want to know current status of H. pylori infection and peptic ulcer in the northern Kaohsiung area.
Methods: We analysed clinical records and questionnaires retrospectively of 164 outpatients (male: 86; female: 78) at E-Da Hospital. The patients suffered from peptic ulcers proven by both endoscopy and CLO test.
Results: H. pylori infection rates of gastric ulcer, duodenal ulcer, and gastric ulcer complicated with duodenal ulcer were 43.69%, 53.19%, and 63.64%, respectively (p＜0.05). In addition, the relative ratios of male to female patients with positive tests were 1.25, 1.5, and 1.1, respectively. Among gastric ulcer patients, those with blood-type O suffered more from H. pylori infection (p＜0.05). However, among duodenal ulcer patients, those with blood-type B suffered more from H. pylori infection (p＜0.05). Among gastric and duodenal ulcer patients, those of Hakka ethnicity suffered more from H. pylori infection (p＜0.05). Among gastric and duodenal ulcer patients, there was no correlation between H. pylori infection and smoking, drinking tea, or non-steroid anti-inflammatory drug usage. However, there was a correlation between H. pylori infection and coffee usage (p＜0.05).
Conclusions: Due to specific geographic and cultural conditions, there could be distinctive presentations of peptic ulcers in the north Kaohsiung area. Better understanding of peptic ulcer status in this part of our country could be meaningful for better preventive medicine.

並列關鍵字

blood type ； H. pylori infection ； peptic ulcer