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【論文摘要】The Effects of Cardiac Rehabilitation on Oxygen Pulse in Patient With Acute Coronary Syndrome

【論文摘要】心臟復健針對急性冠狀動脈徵候群病患氧脈的影響

摘要


Background and Purpose: O_2 pulse is generally considered a reflection of cardiovascular efficiency during exercise as well as a strong predictor of mortality in patients with coronary artery disease. However, there are limited literatures discussing the training effect on the O_2 pulse in patients with acute coronary syndrome (ACS). The purpose of this study was to evaluate the effect of cardiac rehabilitation (CR) program on O_2 pulse and maximum oxygen consumption (VO_2max) in patients with recent ACS. Methods: Patients with ACS status post PCI were enrolled in the study. They were randomized into two groups, including 49 patients (mean age 56.2 ± 8.9 years) in the training group and 41 (mean age 56.7 ± 13.1 years) in the control group. Patients in the training group underwent the CR programs 30 minutes for 36 sessions with a physiotherapist's supervision and patients in the control group only did home-based exercises with self-monitoring. Before and after the exercises training, both groups performed the symptom-limited exercise test with cycling, and their O_2 pulse and VO_2 max were measured. Results: There was no significant difference of O_2 pulse (control group = 12.373, training group = 14.680; p = 0.635) and VO_2 max (control group: 22.178, training group: 20.310; p = 0.129) between the two groups at baseline. After the CR program, the O_2 pulse got significant improvement in the training group (+1.9 ml/bpm, p < 0.001) but decreased in control group (-0.09, p = 0.781) compared with their baselines. In addition, the training group demonstrated significantly greater improvement in VO_2 max than the control group (training group: 5.582, control group: 0.568; p = 0.034). Conclusion: CR programs for 36 sessions were beneficial to improve O_2 pulse and VO_2 max in patients with ACS. Clinical Relevance: Our results provided evidences to support the effectiveness of appropriate CR programs in improving O_2 pulse and VO_2 max in patients with ACS.

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