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運動選手胰島素敏感度之特質

Characteristics of Insulin Sensitivity in Various Types of Athletes

摘要


醣類為運動比賽過程主要的能源,而胰島素敏感度與醣類的吸收與儲存成正比。在臨床醫學上,血糖值廣泛地被作為葡萄糖耐受度受損和第二型糖尿病的預測指標。而大部分男性運動選手皆具正常血糖濃度,其不同空腹胰島素濃度是否可作為評估胰島素敏感度的差異,目前仍未清楚。本研究目的為了解不同空腹胰島素濃度男性運動選手的胰島素阻抗性差異。空腹血糖濃度達正常值範圍內(<100 mg/dl),總計31項465名運動專長選手為研究對象。所有受試者再依空腹胰島素濃度分成三組:低胰島素組(<5 mU/dl, n=146)、中胰島素組(5-9.9 mU/dl, n=218)和高胰島素組(>10 mU/dl, n=101)。本研究結果顯示:一、高胰島素組身體質量指數和BIA體脂肪率屬於體重過重的範圍(BMI: 25.4±0.4; BIA: 22.5±0.7),且兩者具高度正相關(r=0.786, p<.001);二、高胰島素組的胰島素阻抗性(HOMA-IR)為3.95±0.21、中胰島素組為1.56±0.02及低胰島素組為0.77±0.02,各組均達顯著差異(p<.001);三、空腹胰島素和HOMA-IR兩者呈現顯著高度相關(r=0.994, p<.001)。本研究結論顯示身體的胰島素阻抗性隨著體脂肪增加而提高,針對運動選手的代謝適能檢測方面,採用空腹胰島素濃度為檢驗胰島素敏感度的有效的方法。

並列摘要


Fasting plasma glucose is widely used to predict the impaired glucose tolerance and type 2 diabetes in various populations. The difference in fasting insulin levels for evaluating metabolic status in male athletes with normal glucose have not been demonstrated completely. Therefore, we designed this study to evaluate the insulin sensitivity in various types of athletes. In this study total 465 subjects from 31-types of sport events were participated as effective samples. All the subjects with normal plasma glucose (<100mg/dl) were matched for fasting insulin level and assigned them into three groups including: Low fasting insulin level (FIL, <5mU/dl, n=146), Medium FIL (5-9.9mU/dl, n=218), and High FIL (>10mU/dl, n=101). The results of this study showed that both BMI and fat percentage in high FIL group reaches grade-1 overweight, and a significant correlation between two obesity measures (r=0.786, p<.001). A mean HOMA-IR in three groups was significantly different from each other that is 0.77, 1.56, and 3.95 respectively. This results indicates that fasting insulin level in all subjects were significantly associated with HOMA-IR (r=0.994, p<.001). From this data it was concluded that insulin resistance was directly associated with increased body fat. In addition, measurements of both fasting insulin level and obesity standard degree are useful to predict the insulin resistance in various types of male athletes.

並列關鍵字

exercise training BMI insulin level

參考文獻


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