- 期刊
Glassy Cell Carcinoma of the Cervix: A Case Report
子宮頸玻璃狀細胞癌：個例報告
摘要
子宮頸玻璃狀細胞癌是一種很罕見且高惡性度的腫瘤，大約只佔所有子宮頸癌的1-2%。子宮頸玻璃狀細胞癌是一種頗具生物侵襲性的惡性腫瘤，臨床病程變化快速，而且對傳統的治療方式反應不佳，故其預後很差。因其案例數量有限，目前仍無法歸納出最佳的治療準則。我們提出一個子宮頸玻璃狀細胞癌的個例。此患者因異常出血而來求診，子宮頸切片先診斷為子宮頸鱗狀細胞癌。在接受子宮根除性手術與兩側骨盆淋巴節摘除術後，病理診斷意外發現為此種罕見的玻璃狀細胞癌。因其高惡性度，術後我們給予患者合併放射線與化學藥物同步治療。結束合併治療後經二十一個月的檢查追蹤，此患者至目前仍無復發之跡象。
並列摘要
Glassy cell carcinoma (GCC) of the cervix is a rare and highly malignant tumor, accounting for only 1-2% of all cervical carcinomas. This infrequent pathologic subtype is an aggressive biologic tumor associated with a rapid deteriorating clinical course and poor outcome, despite treatment. The number of cases of cervical GCC is too small to draw conclusion about the treatment of choice and survival. A case of cervical GCC is presented here. The patient suffered from post-coital vaginal bleeding. Cervical biopsy revealed squamous cell carcinoma. Radical hysterectomy was performed. Upon a more extensive pathologic exam, glassy cell carcinoma was diagnosed. Concurrent chemoradiation with 3 courses of cisplatin, epirubicin and mitomycin-C (PEM) and 2 courses of weekly cisplatin were given after primary surgical treatment. Post treatment, the patient remains disease free and continues to receive regular follow-up in our clinic.
延伸閱讀
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