目的:本研究的主要目的在於探討心臟電腦斷層血管攝影(CTA)應用於兒童時輻射劑量與影像品質的對應關係。方法:我們利用64切與256切電腦斷層,針對仿1歲兒童的擬人假體進行心臟CTA掃描,掃描程序包含了無心電圖監控、回溯性心電圖監控(retrospectively ECG-gated helical, RGH)以及前導性心電圖監控(prospectively ECG-gated axial, PGA)。在劑量評估部分,我們採用熱發光劑量計量測器官劑量,並計算推得有效劑量以評估病人輻射劑量。在影像品質部份,我們利用影像雜訊大小與訊號對雜訊比值(SNR)評估重建電腦斷層影像的影像品質。結果:針對64切電腦斷層,無心電圖監控與RGH掃描所產生的有效劑量分別為1.85 ± 0.13 mSv與5.78 ± 0.41 mSv;在256切電腦斷層,無心電圖監控、RGH與PGA掃描所產生的有效劑量分別為2.66 ± 0.18 mSv、8.48 ± 0.60 mSv與1.54 ± 0.13 mSv。由影像雜訊與SNR數據發現,無心電圖監控掃描可產生出最好的影像品質,PGA掃描的影像品質較RGH掃描為佳,且PGA掃描的輻射劑量較RGH掃描有81.5%的降幅。結論:整體而言,PGA掃描在平衡兒童心臟CTA的輻射劑量與影像品質上具有良好的表現,吾人相信本研究成果將可對制定低劑量兒童心臟CTA的照影程序及參數設定上提供參考數據。
Objective: The aim of this study was to investigate the impact of imaging protocol on the relationship between radiation exposure and image quality for pediatric cardiac CT angiography (CTA). Methods: A 64-slice CT scanner and a 256-slice CT scanner were used to perform non-gated, retrospectively ECG-gated helical (RGH) and prospectively ECG-gated axial (PGA) techniques on an anthropomorphic phantom simulating a 1-year-old child. The thermoluminescent dosimeters (TLD) were used for dose measurement. For image quality, noise and signal-to-noise-ratio (SNR) were assessed based on regions-of-interest drawn on the reconstructed CT images. Results: In 64-slice CT, the effective doses from TLD measurements were 1.85 ± 0.13 and 5.78 ± 0.41 mSv for non-gated and RGH scans, respectively. In 256-slice CT, the effective doses were 2.66 ± 0.18, 8.48 ± 0.60 and 1.54 ± 0.13 mSv for non-gated, RGH and PGA scans, respectively. The non-gated scans showed the best image quality in terms of noise and SNR. The PGA scans had better image quality than the RGH scans with 81.5% dose reduction. Conclusion: The PGA scan protocol balances radiation exposure and image quality for pediatric cardiac CTA. These results should be helpful for further investigation of dose reduction strategies in pediatric cardiac CTA.