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Case Report: Femoral Chondrosarcoma Following Fracture in a Young Adult Dog

病例報告:年輕成犬股骨骨折後繼發軟骨肉瘤

摘要


一隻1歲9個月齡未絕育之阿富汗獵犬,因為6周前的股骨骨折開始出現左後肢跛行。隨後在骨折部位後方發現一軟組織團塊且有越來越大的趨勢。細針抽取生檢團塊顯示為骨來源之惡性腫瘤。經由髖關節進行左後肢截肢手術。腫瘤團塊之組織病理學診斷結果為軟骨肉瘤。病犬於術後接受化學治療,使用carboplatin和piroxicam進行3個循環的療程。之後的追縱達36個月,期間病患無復發情形且精神食慾皆良好。由此病例得知積極的治療包括手術截肢和輔助化學療法可使股骨軟骨肉瘤病患減低腫瘤復發率及延長存活時間。

關鍵字

軟骨肉瘤 化學療法 骨析

並列摘要


A 1-year- and 9-months-old, intact female, Afghan hound was presented with lameness and a gradual increasing soft-tissue mass in the right rearlimb during the last 6 weeks after femoral fracture. Fine-needle biopsy showed that the lesion was malignant tumor of bone origin. Amputation through disarticulating the coxofemoral joint was conducted. The final diagnosis of chondrosarcoma was based on histologic examination. Subsequently adjuvant chemotherapy with carboplatin and piroxicam were administered for 3 cycles. The dog remained more than 36 months of disease- free interval after surgery followed by adjuvant chemotherapy. In this case, aggressive treatment of femoral chondrosarcoma through amputation followed by adjuvant chemotherapy to prolong disease-free interval as well as survival time is beneficial.

並列關鍵字

chondrosarcoma chemotherapy dog fracture

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