- 期刊
利用踝臂血壓比來預測血液透析病人的死亡率
Ankle-brachial Index as a Predictor for Mortality in Patients with Hemodialysis
摘要
Background. Ankle-brachial index (ABI) is a marker for peripheral artery disease and can predict mortality in hemodialysis patients. However, it is seldom studied in Taiwan, an area with high prevalence of end-stage renal disease. The aim of this study was to investigate the predictors for mortality via using ABI value in patients with hemodialysis in Taiwan. Methods. We enrolled 230 hemodialysis patients in one regional hospital. The mean follow-up period was 1.9 ± 0.4 years. Patients were stratified into three groups according to ABI value (＜ 0.9, ≥0.9 to ＜ 1.3, and ≥1.3). The relative mortality risk was analyzed by Cox-regression methods. Results. Twenty-three deaths were recorded in 230 patients (10.0%). In multivariate forward analysis, abnormal ABI (ABI ＜ 0.9 or ≥1.3) (hazard ratio, 2.776; P = 0.043), and smoking (P = 0.007) were positively associated with overall mortality, and serum creatinine level (P ＜ 0.001) was negatively associated with overall mortality. Conclusions. Our findings show that abnormal ABI predicts for overall mortality in hemodialysis patients. Screening patients with hemodialysis by means of ABI may help to identify a high risk group for increased mortality.
並列摘要
Background. Ankle-brachial index (ABI) is a marker for peripheral artery disease and can predict mortality in hemodialysis patients. However, it is seldom studied in Taiwan, an area with high prevalence of end-stage renal disease. The aim of this study was to investigate the predictors for mortality via using ABI value in patients with hemodialysis in Taiwan. Methods. We enrolled 230 hemodialysis patients in one regional hospital. The mean follow-up period was 1.9 ± 0.4 years. Patients were stratified into three groups according to ABI value (＜ 0.9, ≥0.9 to ＜ 1.3, and ≥1.3). The relative mortality risk was analyzed by Cox-regression methods. Results. Twenty-three deaths were recorded in 230 patients (10.0%). In multivariate forward analysis, abnormal ABI (ABI ＜ 0.9 or ≥1.3) (hazard ratio, 2.776; P = 0.043), and smoking (P = 0.007) were positively associated with overall mortality, and serum creatinine level (P ＜ 0.001) was negatively associated with overall mortality. Conclusions. Our findings show that abnormal ABI predicts for overall mortality in hemodialysis patients. Screening patients with hemodialysis by means of ABI may help to identify a high risk group for increased mortality.
延伸閱讀
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