Atopic dermatitis is a skin disease that difficult to heal and easy to relapse of chronic skin diseases. In this study, using blended massage oil compound (6% (v/v) concentration of lose Plum and 4% (v/v) Roman Chamomile), smear on the affected area in each time day and night about two months. Test results, the compound massage oil can improve the condition of the skin lichenification. Observe the appearance of the skin condition show newborn affected skin condition has improved significantly since the third week. After two months affected lichenification has disappeared, newborn skin in good condition. The main reason is Song Hongmei within Triterpenoids and Sesquiterpene Ketones and Roman Chamomile within Esters can effectively improve the underlying collagen and promote skin regeneration and stratum corneum of the skin to improve skin moisture mitigation sustained inflammation and other symptoms.