預防性抗生素之使用

Prophylactic Use of Antibiotics

譚延輝(Yen-Huei Tarn) ； 徐慈穗(Tzu-Sui Hsu)

《北市醫學雜誌》 3卷5期 (2006/05) Pp. 426-432

摘要

本篇文章在回顧近年來預防性抗生素使用之準則。凡乾淨－污染手術大都建議使用預防性的抗生素，然而抗生素的選擇，第一劑量的給藥時間點，給多長時間等都有規範的制定。若預防性之給藥變成治療性的給藥，則不但浪費醫療資源，還有可能導致抗藥菌株之產生。建議醫院內應建立藥物使用評估之機制，針對預防性抗生素之使用建立回顧性評估的方法學，以提升醫療品質。

關鍵字

預防性抗生素 ； 藥物使用評估 ； 醫療品質

並列摘要

This article reviewed the recent guidelines on prophylactic use of antibiotics. In general, prophylactic antibiotics are recommended to be used in all the clean-contaminated surgeries. In addition, the drug of choice, time of the first dose and duration of therapy were suggested in the guidelines. If cases given therapeutically in stead of prophylactic, not only medical resources are wasted, resistant strain of the bacteria may be induced. It is recommended that medication use evaluation system should be developed in the hospital setting, and continuous quality improvement strategy be implemented in the prophylactic use of antibiotics in several surgical procedures in order to improve the quality of medical care process and outcomes.

並列關鍵字

prophylactic use of antibiotics ； medication use evaluation