Purpose: Team Resource Management (TRM) is a procedure and training system in systems where human error can have devastating effects. Material and Method: This article enhances the ability of medical professionals to used TRM tools in the pain management, such as ”ISBAR”, ”Brief”, ”Huddle” and ”Debrief”. Result: This project aims to significantly improve the quality of pain control (36.8 to 10.7 percent), effective rate is 70.9%. Conclusion: TRM training program not only established a culture of teamwork, but also improved our service quality of cancer care. Moreover, we look forward to sharing this experience as a reference resource in TRM training program of other hospital.