Only some countries could well known by global brands, but most of firms may envy to have one. Why most of global brands come from some particular developed countries, but not ranking by economics entities? Is there any special cultural formula within the global brand? The aims of this research are to investigate the national cultural factors associated with global branding? Based on the cross cultural studies for top 100 brands sample of Interbrand's best global brands 2013 shows that PDI, IDV and LTO dimension of Hofstede's model are associated with the global branding countries. Furthermore, the authors find that some key factors of national cultural dimension have positive or negative impact by different industries. Finally, discuss the implications of these finding for theory and practice implication.