Ta Tong (the Great Harmony) is both traditional and typical in Confucian thought. Jen (Benevolence) is considered as its theoretical basis, and Yi (Righteousness) as its practical strategy. On the benefiting the humankind and the world, Ta Tong thought enables to offer great scholarship. Ta Tong society is the ideal society of human-beings. The Great Harmony of the world is just the human mission and purpose of Confucianism.Nonprofit Enterprise is that through which people devote to concern human life and to assist social life in the light of its benevolence and righteousness. It is a missionary enterprise of merciful altruism. It can offer actual devotions on human social welfare and worldly peace.The mutual complement between the Ta Tong Thought and Nonprofit Enterprise is a great and excellent affair in human social life. The idea of the Great Harmony can help and guide Nonprofit Enterprise to have good researches and developments. The missionary realization of Nonprofit Enterprise is rightly the prospect for the Great Harmony thought.