摘要
早老症（Progeria）又稱作Hutchinson - Gilford progeria syndrome，為一非常罕見且致命的漸進性遺傳疾病，以童年表 老人面貌為其特徵。患童在出生時表現正常，但在一歲前開始出現症狀。除了生長發育遲滯外，尚伴有皮下脂肪的喪失、皮膚、骨骼及心血管組織的改變等，但患童的行動及智力通常正常。在口腔方面，窄小的牙弓常衍伸出其它問題像牙齒排列擁擠、異位萌發或阻生、容易產生牙齦炎及齲齒，同時，也讓日常口腔照護及牙科治療較正常孩童困難許多。本病例為一早老症女童，於8歲時因齲齒及齒列嚴重擁擠而求診，後續在門診下持續治療及追蹤至現今12歲。
並列摘要
Progeria, also known as Hutchinson-Gilford progeria syndrome, is an extremely rare, fatal, and progressive genetic disorder characterized by a distinct aged appearance very early in life. Affected children typically appear normal at birth but begin to demonstrate signs and symptoms within the first year of life. Despite marked retardation of growth, loss of subcutaneous fat, alterations in skin, bone, and cardiovascular tissues are also noted, the patients often retain normal in motor and mental functions. In oral aspect, their shallow recessed jaw often leads to other problems like severe crowding, easy gingiva inflammation and caries, ectopic or failure of eruption and also makes daily care and dental treatment harder than normal children. The case presented is a girl who was diagnoses of progeria. She visit our department due to caries and problems of crowded arch, and has received dental treatment and follow-up till now as she is in her 12 years of age.